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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP17 All Species: 18.48
Human Site: S474 Identified Species: 40.67
UniProt: Q68EM7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q68EM7 NP_001006635.1 881 95437 S474 H T G N D S D S G T L E R K R
Chimpanzee Pan troglodytes XP_510887 881 95444 S474 H T G N D S D S G T L E R K R
Rhesus Macaque Macaca mulatta XP_001090267 877 94245 S470 H T G N D S D S G T L E R K R
Dog Lupus familis XP_547084 898 96108 S479 H T G N D S D S G T L E R K R
Cat Felis silvestris
Mouse Mus musculus Q3UIA2 846 92184 E452 E V E F N V S E A F V P L A T
Rat Rattus norvegicus Q99N37 858 93735 S462 V P L A T P N S N H S S H T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521066 476 51957 P82 K P P A P V L P L E G A A P P
Chicken Gallus gallus XP_414864 881 95496 S475 H T G N E Y D S G T L E R K R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001108378 535 59728 L142 I Q K Q R R H L A K L V L D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VDS5 740 83067 R347 N L Y K D F I R I A E R H S E
Honey Bee Apis mellifera XP_395006 799 89540 W406 V I A P N L I W S P Q E D V N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 91.1 87.5 N.A. 84.9 83 N.A. 27 72.5 N.A. 42.6 N.A. 25.7 31.6 N.A. N.A.
Protein Similarity: 100 99.8 93.1 90.6 N.A. 88.1 86.2 N.A. 34.5 82.9 N.A. 51.1 N.A. 44.3 48 N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 0 6.6 N.A. 0 86.6 N.A. 6.6 N.A. 6.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 13.3 13.3 N.A. 0 93.3 N.A. 6.6 N.A. 13.3 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 19 0 0 0 0 19 10 0 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 46 0 46 0 0 0 0 0 10 10 0 % D
% Glu: 10 0 10 0 10 0 0 10 0 10 10 55 0 0 10 % E
% Phe: 0 0 0 10 0 10 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 46 0 0 0 0 0 46 0 10 0 0 0 10 % G
% His: 46 0 0 0 0 0 10 0 0 10 0 0 19 0 0 % H
% Ile: 10 10 0 0 0 0 19 0 10 0 0 0 0 0 0 % I
% Lys: 10 0 10 10 0 0 0 0 0 10 0 0 0 46 0 % K
% Leu: 0 10 10 0 0 10 10 10 10 0 55 0 19 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 46 19 0 10 0 10 0 0 0 0 0 10 % N
% Pro: 0 19 10 10 10 10 0 10 0 10 0 10 0 10 10 % P
% Gln: 0 10 0 10 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 10 10 0 10 0 0 0 10 46 0 46 % R
% Ser: 0 0 0 0 0 37 10 55 10 0 10 10 0 10 0 % S
% Thr: 0 46 0 0 10 0 0 0 0 46 0 0 0 10 10 % T
% Val: 19 10 0 0 0 19 0 0 0 0 10 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _